| Autor: |
Unosson, Erik, Tsekoura, Eleni K, Engqvist, Håkan, Welch, Ken |
| Zdroj: |
Biomatter; October 2013, Vol. 3 Issue: 4 |
| Abstrakt: |
TiO2photocatalysis can be used to kill surface adherent bacteria on biomaterials, and is particularly interesting for use with percutaneous implants and devices. Its efficiency and safety, however, depend on the activation energy required. This in vitro study investigates synergetic effects against the clinically relevant strains S. epidermidisand S. mutanswhen combining photocatalytic surfaces with H2O2. After 20 min exposure to 0.1 wt% H2O2and UV light on TiO2surfaces, viabilities of S. epidermidisand S. mutanswere reduced by 99.7% and 98.9%, respectively. Without H2O2the corresponding viability reduction was 86% for S. epidermidisand 65% for S. mutans. This study indicates that low concentrations of H2O2can enhance the efficiency of photocatalytic TiO2surfaces, which could potentially improve current techniques used for decontamination and debridement of TiO2coated biomedical implants and devices. |
| Databáze: |
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