| Autor: |
Lan, P., Porco, J. A., Jr., South, M. S., Parlow, J. J. |
| Zdroj: |
Journal of Combinatorial Chemistry; September 2003, Vol. 5 Issue: 5 p660-669, 10p |
| Abstrakt: |
A general method for a polymer-assisted solution-phase (PASP) Mitsunobu reaction using a combination of anthracene-tagged phosphine and polymer-supported azodicarboxylate is reported. The anthracene-tagged phosphine allows for the removal of phosphine/phosphine oxide by sequestration through a chemoselective Diels−Alder reaction with a maleimide resin. The polymer-bound azodicarboxylate facilitates the removal of excess alcohol, reagent, and byproducts by simple filtration. The final pure products are obtained after a simple filtration and concentration. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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