| Autor: |
Oliver, Roy F., Jahoda, Colin A.B. |
| Zdroj: |
Clinics in Dermatology; October-December 1988, Vol. 6 Issue: 4 p74-82, 9p |
| Abstrakt: |
The dermal papilla is established as a permanent and stable population of specialized fibroblasts that first appear as a cellular aggregate that interacts with the epidermis to ensure follicle development. Our experimental findings strongly suggest that thereafter the papilla, in association with the confluent lower dermal sheath, continues to interact with the follicular epidermis with the papilla cells, which retain their aggregative property, undergoing cyclic changes in size and synthetic activities in phase with the hair cycle. In these activities, the lower follicle dermis appears to act as a functional unit17that retains key embryonic characteristics throughout the lifetime of the follicle,39reenacting its inductive influence over follicular epidermis to regulate the profound morphogenetic changes that occur during successive hair cycles and to determine the physical characteristics of the fibers produced. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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