| Autor: |
Liu, Su, Karaganis, Stephen, Mo, Ru-Fan, Li, Xiao-Xiao, Wen, Ruo-Xin, Song, Xue-Jun |
| Zdroj: |
Journal of Pain; July-August 2020, Vol. 21 Issue: 7-8 p836-847, 12p |
| Abstrakt: |
•Intrathecal interferon β (IFNβ) attenuates mechanical allodynia without behavioral deficits.•Interferon-stimulated gene 15 (ISG15) is induced by IFNβ in the spinal cord and mediates analgesic effects.•IFNβ mediated analgesia and induction of ISG15 is potentiated in UBP43−/−mice.•IFNβ treatment inhibits MAPK signaling by ISG15 activation. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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