Four-year follow-up on the Albany experience with intrapleural BCG in lung cancer

Autor: McKneally, Martin F., Maver, Carole, Lininger, Lloyd, Kausel, Harvery W., Mcllduff, Joseph B., Older, Thomas M., Foster, Eric D., Alley, Ralph D.
Zdroj: Journal of Thoracic and Cardiovascular Surgery; April 1981, Vol. 81 Issue: 4 p485-492, 8p
Abstrakt: One hundred sixty-nine patients were entered into randomized controlled studies of intrapleural bacille Calmene Guérin (BCG) immunotherapy after surgical resection of lung cancer. Long-term follow-up of our initial series of BCG-treated patients with Stage I disease continues to indicate that this treatment was superior to that given the control patients. The recurrence rate in the control population was high, 62% at 3 years. The recurrence rate was 33% at 3 years in the BCG-treated group. A negative preoperative tuberculin test and squamous cell histologic type were favorable prognostic factors for BCG-treated patients. The survival of patients with more advanced disease was not improved by BCG immunotherapy.
Databáze: Supplemental Index