Lymph node metastasis in resectable esophageal cancer

Autor: Abe, Shun’ichi, Tachibana, Mitsuo, Shiraishi, Morio, Nakamura, Teruhisa
Zdroj: Journal of Thoracic and Cardiovascular Surgery; August 1990, Vol. 100 Issue: 2 p287-291, 5p
Abstrakt: The prognostic significance of lymph node metastasis was analyzed in 41 patients with locally resectable epidermoid carcinoma of the esophagus. The 5-year survival rate was 50.9% if no metastases or only single node metastasis was present and 29.8% when the lymph node metastasis was confined to one anatomic compartment All patients with metastasis to two nodes died within 4 years of operation, and all with involvement of three nodes or more died within 3 years. Even with no metastases or single node metastasis, three of 22 patients (13.6%) died of recurrence or metastasis or a combination of the two. Although nodal dissection may be beneficial for selected patients, our results indicate that the survival period is short in the presence of a small number of lymph node metastases, even if the local disease is resectable and despite nodal dissection. Cure is unlikely when cervical or abdominal nodes are involved, and a conservative approach may be indicated for such patients.
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