Reaction of 2-Polyfluoroalkylchromones with 1,3,3-Trimethyl-3,4-dihydroisoquinolines and Methylketimines as a Direct Route to Zwitterionic Axially Chiral 6,7-Dihydrobenzo[a]quinolizinium Derivatives and 2,6-Diaryl-4-polyfluoroalkylpyridines

Autor: Sosnovskikh, V. Ya., Usachev, B. I., Sizov, A. Yu., Vorontsov, I. I., Shklyaev, Y. V.
Zdroj: Organic Letters; August 2003, Vol. 5 Issue: 17 p3123-3126, 4p
Abstrakt: 2-Polyfluoroalkylchromones react with 1,3,3-trimethyl-3,4-dihydroisoquinolines to give zwitterionic axially chiral 6,7-dihydrobenzo[a]quinolizinium derivatives in high yields. In addition, performing this reaction with aromatic methylketimines is a simple and convenient synthesis of 2,6-diaryl-4-polyfluoroalkylpyridines.
Databáze: Supplemental Index