| Autor: |
Fernandes, M., Smith, I. Sanford, Weder, A., Kim, K. E., Gould, Anne B., Busby, Patricia, Swartz, C., Onesti, G. |
| Zdroj: |
Clinical Science; January 1975, Vol. 48 Issue: Supplement 2 p181s-184s, 4p |
| Abstrakt: |
1. Prazosin decreases blood pressure in normotensive, renal hypertensive and spontaneous hypertensive rats. The effect is greatest in the last-named. 2. In spontaneously hypertensive rats the decrease in pressure is associated with a decrease in heart rate. 3. In hypertensive patients prazosin decreases blood pressure by decreasing total peripheral resistance with minor effects on cardiac output. 4. Prazosin is effective in the long-term therapy of hypertensive patients, alone and in combination with a diuretic. The effect on blood pressure is the same in the supine and standing position. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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