Abnormal Sodium Transport in Leucocytes from Patients with Essential Hypertension and the Effect of Treatment

Autor: Thomas, R. D., Edmondson, R. P. S., Hilton, P. J., Jones, N. F.
Zdroj: Clinical Science; January 1975, Vol. 48 Issue: Supplement 2 p169s-170s, 2p
Abstrakt: 1. In seventeen patients with untreated essential hypertension the sodium and water contents of leucocytes were significantly increased, whereas the rate constant for ouabain-sensitive sodium efflux was significantly reduced. 2. These abnormalities were not found in fourteen other patients with well-controlled hypertension. 3. Preliminary observations in accelerated hypertension suggest a different pattern of abnormality in leucocyte sodium metabolism.
Databáze: Supplemental Index