| Autor: |
Nussberger, J., Brunner, D. B., Waeber, B., Biollaz, J., Brunner, Hans R. |
| Zdroj: |
Clinical Science; March 1987, Vol. 72 Issue: 3 p387-389, 3p |
| Abstrakt: |
1. In nine normal volunteers, a series of five venous blood samples was obtained before and up to 24 h after converting enzyme inhibition by a single oral dose of enalapril or lisinopril. Plasma renin activity and blood angiotensin I were measured. 2. A close linear relationship was found between the increase in plasma renin activity and the increase in blood angiotensin I. 3. The linear correlation between plasma renin activity and blood angiotensin I remained after converting enzyme inhibition. 4. Thus, the rise in angiotensin I after inhibition of the conversion of angiotensin I to angiotensin II is due to an enhanced release of renin rather than to accumulation of angiotensin I. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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