| Autor: |
Remington, M C, Bashey, R I, Brighton, C T, Jimenez, S A |
| Zdroj: |
Biochemical Journal; November 1984, Vol. 224 Issue: 1 p227-233, 7p |
| Abstrakt: |
Collagen biosynthesis by organ cultures of the hypertrophic zone of calf growth-plate cartilage was studied. It was found that this tissue devotes a large portion of its biosynthetic commitment towards production of a collagen molecule comprising short collagen chains. This collagen is similar to short-chain collagens synthesized by chick-embryo tibiotarsus, rabbit growth-plate cartilage and chick chondrocytes grown in three-dimensional gels. However, in contrast with the collagen synthesized in these three systems, the short-chain collagen synthesized by calf growth-plate hypertrophic cartilage is stabilized by disulphide bonds localized within the pepsin-resistant triple-helical collagenous domains of these molecules. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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