Acute effects of glucagon on citrulline biosynthesis

Autor: Rabier, D, Briand, P, Petit, F, Parvy, P, Kamoun, P, Cathelineau, L
Zdroj: Biochemical Journal; September 1982, Vol. 206 Issue: 3 p627-631, 5p
Abstrakt: Mitochondria isolated from livers of rats fed on different diets showed altered capacity to synthesize citrulline. Glucagon, 15 min after injection, increases citrulline biosynthesis, except after the high-protein diet. A significant correlation between citrulline biosynthesis and N-acetylglutamate content with and without glucagon treatment was shown when rats were fed on a standard or a carbohydrate diet. Different diets modified carbamoyl phosphate synthetase I (EC 6.3.4.16) and N-acetylglutamate synthase (acetyl-CoA:L-glutamate N-acetyltransferase, EC 2.3.1.1) activities. Glucagon did not modify these activities.
Databáze: Supplemental Index