| Autor: |
Clark, D G, Brinkman, M, Filsell, O H, Lewis, S J, Berry, M N |
| Zdroj: |
Biochemical Journal; March 1982, Vol. 202 Issue: 3 p661-665, 5p |
| Abstrakt: |
(Na+ + K+)-dependent ATPase activity, heat production and oxygen consumption were increased by 59%, 62% and 75% respectively in hepatocytes from tri-iodothyronine-treated rats. Ouabain at concentrations of 1 and 10 mM decreased oxygen uptake by 2-8% in hepatocytes from euthyroid rats and by 5-15% in hepatocytes from hyperthyroid animals. Heat output was decreased by 4-9% with the glycoside in isolated liver parenchymal cells from the control animals and by 11% in the cells from the tri-iodothyronine-treated animals. These results do not support the hypothesis that hepatic (Na+ + K+)-ATPase plays a major role in increased heat production in hepatocytes from hyperthyroid rats. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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