Effect of glucose on carbohydrate synthesis from alanine or lactate in hepatocytes from starved rats

Autor: Solanki, K, Nyfeler, F, Moser, U K, Walter, P
Zdroj: Biochemical Journal; October 1980, Vol. 192 Issue: 1 p377-380, 4p
Abstrakt: In hepatocytes from starved rats, 10mM-glucose suppressed in incorporation of 2mM labelled alanine into glucose+glycogen by more than 40%, whereas no inhibition was observed with labelled lactate as substrate. Addition of glycerol instead of glucose did not show this inhibition. The inhibitory effect could also be demonstrated in label-free experiments.
Databáze: Supplemental Index