N-formyl-l-methionine deformylase activity in human leucocytes and platelets

Autor: Ackerman, S K, Douglas, S D
Zdroj: Biochemical Journal; September 1979, Vol. 182 Issue: 3 p885-887, 3p
Abstrakt: Extracts of human neutrophils, lymphocytes and platelets enzymically deformylate N-formyl-L-methionine. Enzyme activity is stimulated by Co2+, inhibited by bivalent-cation chelators and unaffected by inhibitors of serine, thiol and carboxyl proteinases. Leucocyte or platelet N-formylmethionine deformylase may be important in modulation of neutrophil responses to chemoattractant formylmethionyl peptides or similar compounds.
Databáze: Supplemental Index