Ribozyme-catalysed carbon-carbon bond formation

Autor: Jäschke, A., Stuhlmann, F., Bebenroth, D., Keiper, S., Wombacher, R.
Zdroj: Biochemical Society Transactions; November 2002, Vol. 30 Issue: 6 p1137-1140, 4p
Abstrakt: Numerous RNA molecules with new catalytic properties have been isolated from synthetic combinatorial libraries. A broad range of chemical reactions is catalysed, and nucleic acids can accelerate bond formation between small organic substrates. This review focuses on carbon-carbon bond formation accelerated by in vitro selected ribozymes. Mechanistic investigations and structure-function relationships are discussed.
Databáze: Supplemental Index