| Autor: |
KING, ROBERT A., RIDDLE, MARK A., CHAPPELL, PHILLIP B., HARDIN, MAUREEN T., ANDERSON, GEORGE M., LOMBROSO, PAUL, SCAHILL, LARRY |
| Zdroj: |
Journal of the American Academy of Child & Adolescent Psychiatry; March 1991, Vol. 30 Issue: 2 p179-186, 8p |
| Abstrakt: |
Self-injurious ideation or behavior appeared de novo or intensified during fluoxetine treatment of obsessive-compulsive disorder in six patients, age 10 to 17 years old, who were among 42 young patients receiving fluoxetine for obsessive-compulsive disorder at a university clinical research center. These symptoms required the hospitalization of four patients. Before receiving fluoxetine, four patients had major risk factors for self-destructive behavior including depression or prior suicidal ideation or self-injury. Three hypotheses concerning the apparent association between fluoxetine and these self-injurious phenomena are discussed: (1) coincidence; (2) disorganization of vulnerable individuals secondary to drug-induced activation; and (3) a specific serotonergic-mediated effect on the regulation of aggression. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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