| Autor: |
Mathsyaraja, Haritha, Freie, Brian, Cheng, Pei-Feng, Babaeva, Ekaterina, Catchpole, Jonathen T., Janssens, Derek, Henikoff, Steven, Eisenman, Robert N. |
| Zdroj: |
Genes & Development; 2019, Vol. 33 p1252-1264, 13p |
| Abstrakt: |
Here, Mathsyaraja et al. demonstrate that B-cell-specific deletion of Max has a modest effect on B-cell development but completely abrogates Eµ-Myc-driven lymphomagenesis. Their findings provide new insights into Myc autoregulation, which is critical for lymphomagenesis yet partly dispensable for normal development. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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