| Autor: |
González-Vargas, Pedro Miguel, Thenier-Villa, José Luis, Sanromán Álvarez, Pablo, Serantes Combo, Alexandre, Calero Félix, Lourdes, Galárraga Campoverde, Raúl Alejandro, Azevedo González, Eva, Martín-Gallego, Álvaro, Martínez-Rolan, Rosa, de la Lama Zaragoza, Adolfo, Conde Alonso, Cesáreo |
| Zdroj: |
Neurocirugía; January-February 2020, Vol. 31 Issue: 1 p14-23, 10p |
| Abstrakt: |
Hemangiopericytoma and Solitary Fibrous Tumor are tumors with low incidence. They have a tendency to recur locally and to metastasize. The WHO integrated both tumors into a new entity but one of the pending issues is to demonstrate the effectiveness of surgery plus complementary radiotherapy (RT) and standardize the use of it. We reviewed the data from 10 years. We assessed pathologic and radiologic characteristics. The operation records were evaluated to determine the features and extent of tumor resection. We compared the outcomes in patients using or not RT. The mean follow-up was 74.8 months, with a range of 12 and 210 months. The population included 3 males (30%) and 7 females (70%). The most common location was brain convexity (30%), the remaining were cervical and lumbar spine, sacrum, intraventricular, torcular, sphenoid ridge and intraorbital. Postoperative external beam radiotherapy was delivered in 7 patients (70%), the criteria were a partial resection or WHO II and III histological grades. 2 patients developed local recurrences at 12 and 19 months after initial surgery. 1 patient underwent 2 surgeries, and the other, 4 surgeries. The mean recurrence free survival rate was 15.5 months. Distant metastases were found in 4 patients. 3 of the 10 patients died. Five-year overall survival rate was 66% and mean overall survival was 76 months. A safe and complete resection in the first surgery is the most important prognostic factor. Complementary RT can be helpful, even in cases of complete resection in WHO low-grade. |
| Databáze: |
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