| Autor: |
Grundy, Richard, Hulse, Richard Philip |
| Zdroj: |
Current Opinion in Physiology; October 2019, Vol. 11 Issue: 1 p58-61, 4p |
| Abstrakt: |
Research advances have led to an increased survival for childhood cancer and importantly, recognition of the quality of that survivorship. Unfortunately, adult survivors of childhood cancers often suffer an array of adverse health related side-effects arising from necessary treatment. A highly prevalent complication that occurs many years after cessation of treatment is the long-term alterations in sensory perception. This is typically presented as pain in a young adult, with the number of patients reporting pain becoming an indeterminate complication. Recent investigations present the development of rodent models that allow the exploration of causative factors that initiate childhood cancer survivorship pain. Here we provide an overview that highlights the significant burden that survivorship pain has upon paediatric cancer patients. |
| Databáze: |
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