Rotatory behavior induced in nigra-lesioned rats by n-propylnoraporphine, apomorphine, and levodopa

Autor: Mendez, J.S., Cotzias, G.C., Finn, B.W., Dahl, K.
Zdroj: Life Sciences; June 1975, Vol. 16 Issue: 11 p1737-1742, 6p
Abstrakt: The induction of rotatory behavior by N-propylnoraporphine, apomorphine, and levodopa (the last given with a peripheral metabolic inhibitor) was studied in rats with unilateral nigral lesions produced with 6-OH dopamine. Within the dose ranges studied, N-propylnoraporphine had longer lasting effects than did the other two drugs, and its activity was significantly increased by atropine.
Databáze: Supplemental Index