| Autor: |
TALA, PEKKA |
| Zdroj: |
European Journal of Endocrinology; August 1952, Vol. 10 Issue: 4, Number 4 Supplement 1 pS9-S104, 96p |
| Abstrakt: |
Our knowledge of the interrelation between the thyroid and pituitary glands derives its origin from the observation by Nièpce(1851) of hypertrophy of the anterior pituitary gland in man and animals with endemic goiter or cretinism. Rogowitsch(1889) demonstrated that following total thyroidectomy the pituitary gland of dogs and rabbits became enlarged and showed microscopically determinable changes. Simmonds(1914) reported the results of observation of persons with spontaneous necrosis of the pituitary gland. These symptoms of Simmonds's disease have been of importance in our learning to understand the interrelation between the thyroid and pituitary glands, since this condition in humans is equivalent to total hypophysectomy.Smith and Smith(1922) were the first to demonstrate that the hypophysis elaborates a thyroid-stimulating factor. They were able to restore to the former state and re-activate the atrophied thyroid of hypophysectomized frog tadpoles by parenteral treatment of the animals with an extract of the |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
