Sanguinarine in the blood and urine of cases of epidemic dropsy

Autor: Shenolikar, I.S., Rukmini, C., Krisnamachari, K.A.V.R., Satayanarayana, K.
Zdroj: Food and Cosmetics Toxicology; October 1974, Vol. 12 Issue: 5-6 p699-702, 4p
Abstrakt: During a recent outbreak of epidemic dropsy at Sirpur-Kagaznagar, Andhra Pradesh, samples of blood and urine were obtained from patients severely affected with symptoms of the disease and oil samples collected from their households. Screening of these samples for the presence of sanguirine indicated that all households. samples of oil, all but one of the 22 random urine samples and two of the 22 blood samples taken were positive. The two blood samples contained 4·7 and 27·3 μg sanguinarine/100 ml serum. The levels of sanguirine found in the edible oils and the finding that pure argemone oil contained 5·4 mg sanguiranine/ml together indicated that the degree of adulteration of the edible samples with argemone oil ranged from 0·16 to 2·2%.
Databáze: Supplemental Index