Expression of BK channels and Na+-K+pumps in the apical membrane of lacrimal acinar cells suggests a new molecular mechanism for primary tear-secretion

Autor:	Almássy, János, Diszházi, Gyula, Skaliczki, Marianna, Márton, Ildikó, Magyar, Zsuzsanna Édua, Nánási, Péter P., Yule, David I.
Zdroj:	The Ocular Surface; April 2019, Vol. 17 Issue: 2 p272-277, 6p
Abstrakt:	Primary fluid secretion in secretory epithelia relies on the unidirectional transport of ions and water across a single cell layer. This mechanism requires the asymmetric apico-basal distribution of ion transporters and intracellular Ca2+signaling. The primary aim of the present study was to verify the localization and the identity of Ca2+-dependent ion channels in acinar cells of the mouse lacrimal gland.
Databáze:	Supplemental Index
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