Boranes in synthesis. 4. Hydroboration of enamines derived from 2-norbornanone. Synthesis of endo-3-(dialkylamino)-exo-2-norbornanols and endo-2-(dialkylamino)norbornanes

Autor: Goralski, Christian T., Hasha, Dennis L., Nicholson, Lawrence W., Singaram, Bakthan
Zdroj: Tetrahedron Letters; July 1994, Vol. 35 Issue: 29 p5165-5168, 4p
Abstrakt: The hydroboration of the enamines derived from 2-norbornanone with BMS followed by methanolysis and oxidation with basic hydrogen peroxide afforded moderate yields of the corresponding endo-3-(dialkylamino)-exo-2-norbornanols. Hydroboration with 9-BBN followed by methanolysis gave excellent yields of the corresponding endo-2-(dialkylamino)norbornanes.
Databáze: Supplemental Index