| Autor: |
Niewenhuis, Robert J., Fende, Peggy L. |
| Zdroj: |
Biology of Reproduction; August 1978, Vol. 19 Issue: 1 p1-7, 7p |
| Abstrakt: |
An ultrastructural study on the protective effect of selenium upon cadmium-induced damage to the vasculature of scrotal and cryptorchid testes of the rat was performed. Pretreatment with selenium injected s.c. prevented the progressive time related changes to the endothelial cell junctions seen at 3, 6 and 9 h after the s.c. injection of cadmium alone. This suggests an inactivation of cadmium by selenium prior to its transit across the endothelium. The cryptorchid condition made no noticeable difference upon the protective effect of selenium even though the cryptorchid testis is more susceptible to cadmium toxicity. An interaction between cadmium and calcium may be responsible for the breakdown of the cell junctions. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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