| Autor: |
Brandão-Filho, Sinval P., Campbell-Lendrum, Diarmid, Brito, Maria E.F., Shaw, Jeffrey J., Davies, Clive R. |
| Zdroj: |
Transactions of the Royal Society of Tropical Medicine & Hygiene; September 1999, Vol. 93 Issue: 5 p488-494, 7p |
| Abstrakt: |
Health service records for north-east Brazil suggest a consistent rise in numbers of cases of cutaneous leishmaniasis due to Leishmania (Viannia) braziliensisover the past decade. In a study site in Pernambuco, prospective, cross-sectional and retrospective epidemiological surveys of infection (a positive Montenegro skin test response) and/or clinical symptoms confirmed a high current force of infection (0·092/year), and an approximately 10-fold increase in transmission during the last 10 years. Cross-sectional analysis indicated that the incidence rate among children (aged ? 15 years) was lower than that among adult immigrants exposed for similar time periods, but there was no apparent difference in transmission rate according to gender. Coupled with the known behaviour of the local sandfly vector, Lutzomyia whitmani, this suggests that most people are infected outside their houses, rather than either indoors or while visiting remnant rainforest. The estimated proportion of infections which lead to cutaneous lesions (0·81–0·87) is relatively high for L. braziliensisareas. However, an unusually low proportion of clinical infections (0·0042) apparently leads to metastasis. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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