Direct targeting of Gαqand Gα11oncoproteins in cancer cells

Autor: Annala, Suvi, Feng, Xiaodong, Shridhar, Naveen, Eryilmaz, Funda, Patt, Julian, Yang, JuHee, Pfeil, Eva M., Cervantes-Villagrana, Rodolfo Daniel, Inoue, Asuka, Häberlein, Felix, Slodczyk, Tanja, Reher, Raphael, Kehraus, Stefan, Monteleone, Stefania, Schrage, Ramona, Heycke, Nina, Rick, Ulrike, Engel, Sandra, Pfeifer, Alexander, Kolb, Peter, König, Gabriele, Bünemann, Moritz, Tüting, Thomas, Vázquez-Prado, José, Gutkind, J. Silvio, Gaffal, Evelyn, Kostenis, Evi
Zdroj: Science Signaling; March 2019, Vol. 12 Issue: 573
Abstrakt: Inhibition of constitutively activated, oncogenic G proteins inhibits uveal melanoma tumor growth in mice.
Databáze: Supplemental Index