Chemical Composition and Antibacterial Activity of Angelica archangelicaRoot Essential Oil

Autor: Aćimović, Milica G., Pavlović, Snežana Đ., Varga, Ana O., Filipović, Vladimir M., Cvetković, Mirjana T., Stanković, Jovana M., Čabarkapa, Ivana S.
Zdroj: Natural Product Communications; February 2017, Vol. 12 Issue: 2
Abstrakt: Roots of wild growing Angelica archangelicaL. from Mt. Ozren (Serbia) were subjected to hydrodistillation and GC-MS analysis. The roots contained 0.10% of essential oil with α-pinene (29.7%), δ-3-carene (14.2%), and a mixture of β-phellandrene and limonene (13.2%) as main compounds. The modified resazurin microtiter-plate assay was used to evaluate the antibacterial activity of the essential oil against Staphylococcus aureusand Escherichia coli. The minimum inhibitory concentration (MIC) values were 14.2 μL/mL for S. aureusand 28.4 μL/mL for E. coli, while the minimum bactericidal concentrations (MBC) were 56.8 μL/mL and 113.6 μL/mL, respectively. According to the obtained results, the angelica root essential oil can be applied as a natural preservative in food and as a natural antibiotic for the treatment of several infectious diseases caused by these two bacteria.
Databáze: Supplemental Index