Overexpression of Urinary Plasminogen Activator (uPA) Protein and mRNA in Thyroid Carcinogenesis

Autor: Chu, Quyen D, Hurd, Thelma C, Harvey, Shashi, Martinick, Maisie, Markus, Gabor, Tan, Dongfeng, Gibbs, John F, Loree, Thom
Zdroj: Diagnostic Molecular Pathology; December 2004, Vol. 13 Issue: 4 p241-246, 6p
Abstrakt: Urinary plasminogen activator (uPA), a protease, is one of the critical components of tumor invasion and metastasis. Its expression in thyroid carcinoma and potential role in thyroid tumorigenesis are unknown. The objective of this study was to determine whether uPA is differentially expressed in benign and malignant thyroid tumors.
Databáze: Supplemental Index