Reversal of acute tacrolimus-induced renal vasoconstriction by theophylline in rats

Autor: McLaughlin, Gwenn E., Kashimawo, Lutifat A., Steele, Bernard W., Kuluz, John W.
Zdroj: Pediatric Critical Care Medicine; July 2003, Vol. 4 Issue: 3 p358-362, 5p
Abstrakt: To determine whether theophylline, a nonselective adenosine receptor antagonist and phosphodiesterase inhibitor, reverses the acute declines in renal blood flow and glomerular filtration rate induced by high-dose tacrolimus in rats.
Databáze: Supplemental Index