Autor: |
IKEGAMI, MACHIKO, HESTERBERG, TOM, NOZAKI, MASAHIKO, ADAMS, FORREST H. |
Zdroj: |
Pediatric Research (Ovid); March 1977, Vol. 11 Issue: 3 p178-181, 4p |
Abstrakt: |
The pressure-volume (PV) characteristics of 21 adult rat lungs were examined before and after lung washing after which natural or synthetic (dipalmitoyl lecithin (DPL)) surfactant was administered by either an ultrasonic nebulizer or instilled directly into the trachea. Lungs receiving surfactant by nebulization were ventilated at a rate of 40/min at 20 cm H2O peak inspiratory pressure and with 7 cm H2O positive end expiratory pressure (PEEP) for 2 hr. Lungs receiving surfactant by instillation were ventilated for 5 min in a fashion similar to the nebulization study; then a final PV curve was obtained. |
Databáze: |
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