Endotoxemia in the Rhesus Monkey

Autor: FISER, R. H., DENNISTON, J. G., BEISEL, W. R.
Zdroj: Pediatric Research (Ovid); January 1974, Vol. 8 Issue: 1 p13-17, 5p
Abstrakt: Experimentally induced endotoxemia in the rhesus monkey produced a two- to fourfold increase in plasma triglyceride concentration; glucose administration partially prevented this rise. Plasma free fatty acid and phospholipid values were depressed 40–50 of control values whereas cholesterol values were unchanged. Endotoxin-treated monkeys displayed slowed glucose disappearance (K values, 2.2 versus1.1) and higher levels of sugar in blood when given glucose (72 ± 8 mg/100 ml versus151 ± 11 mg/100 ml). These studies indicate that endotoxin has a marked effect on the pattern of substrate utilization by the host.
Databáze: Supplemental Index