| Abstrakt: |
This study was designed to investigate the renin-angiotensin system in the fetal lamb. Simultaneous measurements of plasma renin activity (PRA) were carried out in seven acute fetal-maternal sheep preparations at 91, 100, 104, 112, 124, 142, and 145 days of gestational age, respectively (term 145 days). The mean fetal PRA in this group was 4.87 mμ/ml as compared with 1.58 mμ/ml for the maternal plasma. PRA was also measured simultaneously in three intrauterine nonstressed fetuses. Six days after insertion of catheters, the fetal PRA was 9.0, 9.2, and 8.75 mμ/ml, respectively, and the maternal PRA was 0.4, 4.5, and 3.75 mμ/ml, respectively. |
