| Autor: |
BRANS, YVES W., ANDREW, DONNA S., DUTTON, ELISABETH B., SCHWARTZ, CONNIE A., CAREY, K.D |
| Zdroj: |
Pediatric Research (Ovid); April 1989, Vol. 25 Issue: 4 p377-382, 6p |
| Abstrakt: |
Dilution kinetics of markers commonly used for estimation of body water content and distribution in perinatal medicine (/j-aminohippurate, inulin, antipyrine, H2'8O, bromide, and T1824) were studied in pregnant and neonatal baboons. Amniotic fluid concentrations of /?-aminohippurate and inulin decreased exponentially after intraamniotic injection of these markers; from 2-24 h after injection, concentrations decreased linearly on semilogarithmic plot (r0.96-1.00). Plasma concentrations of antipyrine decreased exponentially during the first 60 min after intravenous injection, then linearly from 1-5 h (r0.92-0.90). Plasma concentrations of I8O decreased linearly from 1-6 h after injection in three or four cases (r0.94-0.99). Plasma concentrations of bromide decreased during the first 2 h after injection, then stabilized for at least 3 h. Plasma concentrations of T1824 decreased linearly from 10-60 min after intravenous injection (r0.97- 1.00). Then the decline became exponential until 5 h. These data allow us to make specific recommendations regarding the optimal time and method of amniotic fluid and blood sampling during body water studies |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
