Integrinligand interactions

Autor: Kanazashi, Shulchi, Sharma, Pal C., Arnaout, Amin M.
Zdroj: Current Opinion in Hematology; January 1997, Vol. 4 Issue: 1 p67-74, 8p
Abstrakt: Integrins provide cells with critical means of communication with their microenvironments. By linking events at the cell surface to a dynamic cytoskeletonsignaling complex, integrins enable cells to rapidly modify their mechanical and genetic machinery in response to environmental cues. This review highlights major advances made in understanding the structural basis of integrinligand interactions and their regulation.
Databáze: Supplemental Index