| Autor: |
Szuba, Martin P., Amsterdam, Jay D., Fernando, Antonio T., Gary, Keith A., Whybrow, Peter C., Winokur, Andrew |
| Zdroj: |
Journal of Clinical Psychopharmacology; August 2005, Vol. 25 Issue: 4 p325-330, 6p |
| Abstrakt: |
Thyrotropin-releasing hormone (TRH) is a tripeptide that produces endocrine and behavioral effects in animals and humans. Some studies have shown transient antidepressant activity after morning administration of TRH. We hypothesized that nocturnal administration of TRH, when the circadian sensitivity of the TRH receptor is at its peak, may result in a more robust antidepressant effect. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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