Nutrient absorption

Autor: Kumar, N Suresh, Soued, Mounzer, Mansbach, Charles
Zdroj: Current Opinion in Gastroenterology; March 1996, Vol. 12 Issue: 2 p122-128, 7p
Abstrakt: During the past year, the intestine was shown to compete with the liver for chylomicron remnant uptake, likely primarily by the low-density lipoprotein receptors that were shown to be present on the basal membranous surface of the enterocytes. The surfactant-like particles that are present on the surface of enterocytes arrive there from the basolateral space by way of the tight junctions between cells. Cells transfected with cholesteryl ester hydrolase greatly increased cholesterol uptake. Glutamine was shown to inhibit glucose oxidation at the level of the Krebs cycle. A mouse with a disease similar to cystic fibrosis was generated. Bile salts were shown to increase iron absorption in the small intestine, and the absorbed iron was transported across the cell in part by lactoferrin. Lactase-phlorhizin hydrolase and the Na-dependent bile acid transporter were shown to undergo developmental changes.
Databáze: Supplemental Index