Autor: |
Newberry, Benjamin H., Frankie, Gary, Beatty, Patricia Ann, Maloney, Barbara D., Gilchrist, J. C. |
Zdroj: |
Psychosomatic Medicine (Ovid); July 1972, Vol. 34 Issue: 4 p295-303, 9p |
Abstrakt: |
This paper presents four experiments dealing with the effects of longterm electric shock stress on rat mammary tumors induced by 7,12dimethylbenzaanthracene. A pilot experiment suggested, contrary to expectations based on Soviet reports, a trend for severe stress to inhibit tumor induction as measured by the number of palpable tumors. A second experiment demonstrated that severe shock stress applied for 85 consecutive days produced a reduction in number of tumors, higher adrenal weights and lower ovary weights relative to controls. Application of the same stress regimen for 40 days also reduced tumor count, while 25day stress did not significantly influence numbers. In no case did the stressor significantly affect average tumor size. |
Databáze: |
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