CONVERSION OF RECURRENT DELTA-POSITIVE HEPATITIS B INFECTION TO SERONEGATIVITY WITH FAMCICLOVIR AFTER LIVER TRANSPLANTATION

Autor: Klein1, Michael, 2, Geoghegan1, Justin, Schmidt1, Karl, Böckler1, Dittmar, Korn3, Klaus, Wittekind4, Christian, Scheele1, Johannes
Zdroj: Transplantation; July 1997, Vol. 64 Issue: 1
Abstrakt: Recurrent hepatitis B infection after liver transplantation is associated with poor graft and patient survival. Famciclovir is a nucleoside with virostatic action in hepatitis B infection. We report the case of a 51-year-old patient who developed recurrent delta-positive hepatitis B infection after liver transplantation. After famciclovir treatment, he became seronegative for hepatitis B early and hepatitis B surface antigens and developed protective anti-hepatitis B surface antibody titers.
Databáze: Supplemental Index