ANTAGONIZING LEUKOTRIENE B4RECEPTORS DELAYS CARDIAC ALLOGRAFT REJECTION IN MICE

Autor: Weringer, Elora J., Perry, Bret D., Sawyer, Perry S., Gilman, Steven C., Showell, Henry J.
Zdroj: Transplantation; March 1999, Vol. 67 Issue: 6 p808-815, 8p
Abstrakt: Allograft rejection is a cellular immunological/inflammatory response that is, in part, directed by potent proinflammatory mediators. This study was designed to test the hypothesis that leukotriene B4(LTB4) may have a role in graft rejection and that LTB4receptor antagonists may be clinically useful in the treatment of allograft rejection.
Databáze: Supplemental Index