INDUCTION OF ORGAN DYSFUNCTION AND UP-REGULATION OF INFLAMMATORY MARKERS IN THE LIVER AND KIDNEYS OF HYPOTENSIVE BRAIN DEAD RATS A MODEL TO STUDY MARGINAL ORGAN DONORS1,2

Autor: Hoeven, Joost A. B. van der, Ploeg, Rutger J., Postema, Folkert, Molema, Ingrid, de Vos, Paul, Girbes, Armand R. J., Suylichem, Paul T.R. van, van Schilfgaarde, Reinout, Horst, Gert J. Ter
Zdroj: Transplantation; December 1999, Vol. 68 Issue: 12 p1884-1890, 7p
Abstrakt: Marginal donors exposed to the full array of effects induced by brain death are characterized by low success rates after transplantation. This study examined whether organs from marginal brain dead animals show any change in organ function or tissue activation making them eventually more susceptible for additional damage during preservation and transplantation.
Databáze: Supplemental Index