| Autor: |
Chen, Wenhau, Bennett, C. Frank, Wang, Mou-Er, Dragun, Duska, Tian, Ling, Stecker, Kim, Clark, James H., Kahan, Barry D., Stepkowski, Stanislaw M. |
| Zdroj: |
Transplantation; September 1999, Vol. 68 Issue: 6 p880-887, 8p |
| Abstrakt: |
We have previously shown that phosphorothioate intercellular adhesion molecule (ICAM)-1 antisense oligodeoxynucleotide (oligo) IP-9125 blocks the expression of rat ICAM-1 mRNA in rat L2 cells. A single ex situ perfusion of grafts with unformulated IP-9125, suspended in Euro-Collins solution, prolonged the survival of kidney allografts in rats. The present experiments examined whether perfusion of kidneys with unformulated IP-9125 prevents ischemic/reperfusion injury. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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