PANCREATIC ISLET XENOGRAFT TOLERANCE AFTER SHORT-TERM COSTIMULATION BLOCKADE IS ASSOCIATED WITH INCREASED CD4 T CELL APOPTOSIS BUT NOT IMMUNE DEVIATION1, 2
Autor: | Lehnert, Anne M., Yi, Shounan, Burgess, Jane S., O’Connell, Philip J. |
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Zdroj: | Transplantation; March 2000, Vol. 69 Issue: 6 p1176-1185, 10p |
Abstrakt: | Our purpose was to determine if short-term inhibition of the CD40/CD40L and CD28/B7 costimulatory pathways was capable of inducing specific unresponsiveness to pancreatic islet xenografts and to ascertain the mechanism of tolerance induction. |
Databáze: | Supplemental Index |
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