LACK OF CROSS-SPECIES TRANSMISSION OF PORCINE ENDOGENOUS RETROVIRUS INFECTION TO NONHUMAN PRIMATE RECIPIENTS OF PORCINE CELLS, TISSUES, OR ORGANS1

Autor: Switzer, William M., Michler, Robert E., Shanmugam, Vedapuri, Matthews, Aprille, Hussain, Althaf I., Wright, Anthony, Sandstrom, Paul, Chapman, Louisa E., Weber, Collin, Safley, Susan, Denny, Roger R., Navarro, Albert, Evans, Valerie, Norin, Allen J., Kwiatkowski, Pawel, Heneine, Walid
Zdroj: Transplantation; April 2001, Vol. 71 Issue: 7 p959-965, 7p
Abstrakt: Nonhuman primates (NHPs) have been widely used in different porcine xenograft procedures inevitably resulting in exposure to porcine endogenous retrovirus (PERV). Surveillance for PERV infection in these NHPs may provide information on the risks of cross-species transmission of PERV, particularly for recipients of vascularized organ xenografts for whom data from human clinical trials is unavailable.
Databáze: Supplemental Index