LONG-TERM ALLOGRAFT ACCEPTANCE INDUCED BY SINGLE DOSE ANTI-LEUKOCYTE COMMON ANTIGEN (RT7) ANTIBODY IN THE RAT1

Autor: Ko, Saiho, Jäger, Mark D., Tsui, Tung-Yu, Deiwick, Andrea, Dinkel, Astrid, Rohde, Frank, Dahlke, Marc H., Lauth, Oliver, Wonigeit, Kurt, Schlitt, Hans J.
Zdroj: Transplantation; April 2001, Vol. 71 Issue: 8 p1124-1131, 8p
Abstrakt: In clinical organ transplantation monoclonal antibodies (mAb) to different surface molecules of immunocompetent cells become integral parts of the immunosuppressive therapy. In this study, a mAb against the rat leukocyte common antigen CD45 (RT7) was tested for its immunosuppressive potency after a single perioperative injection.
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