INTERLEUKIN-15 IS THE MAIN MEDIATOR OF LYMPHOCYTE PROLIFERATION IN CULTURES MIXED WITH HUMAN KIDNEY TUBULAR EPITHELIAL CELLS1

Autor: Lewis, Eli, Weiler, Michal, Chaimovitz, Cidio, Douvdevani, Amos
Zdroj: Transplantation; September 2001, Vol. 72 Issue: 5 p886-890, 5p
Abstrakt: Interleukin- (IL) 15 is a potent non-T cell-derived cytokine with IL-2-like activities. Elevated levels of IL-15 expression were observed in biopsies of acutely rejected human kidney grafts. We tested the role of IL-15 in mixed lymphocyte kidney reaction (MLKR) and the effects of immunosuppressive drugs on this reaction.
Databáze: Supplemental Index