| Autor: |
Gleit, Zachary L., Cameron, Andrew M., Fuchimoto, Yasushi, Melendy, Elizabeth, Monajati, Leila, Coburn, Rebecca C., Sachs, David H., Huang, Christene A. |
| Zdroj: |
Transplantation; November 2002, Vol. 74 Issue: 9 p1260-1266, 7p |
| Abstrakt: |
T-cell chimerism predominates in miniature swine receiving hematopoietic-cell transplantation without myelosuppressive conditioning. Several chimeric recipients have become hyporesponsive to donor-major histocompatibility complex (MHC) in vitro and accepted donor-matched renal transplants without immunosuppression. However, some retained antidonor in vitro responses and subsequently rejected donor renal allografts despite the persistence of peripheral blood chimerism. In this study, we characterize the donor cells in both “tolerant” and “nontolerant” chimeric miniature swine. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
