Autor: |
Alho, Hanni S., Maasilta, Paula K., Harjula, Ari L. J., Hämmäinen, Pekka, Salminen, Jukka, Salminen, Ulla-Stina |
Zdroj: |
Transplantation; August 2003, Vol. 76 Issue: 3 p516-523, 8p |
Abstrakt: |
In posttransplant obliterative bronchiolitis (OB), the major pathologic features are inflammation, epithelial cell injury, fibrosis, and obliteration of the small airways. Tumor necrosis factor (TNF)- is a cytokine known to mediate and augment the inflammatory reaction and to enhance fibroblast proliferation. We assessed the role of TNF- in the development of OB in our heterotopic porcine bronchial transplantation model. |
Databáze: |
Supplemental Index |
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