Homozygous familial hypercholesterolemia specific indication for domino liver transplantation

Autor: Popescu, Irinel, Simionescu, Maya, Tulbure, Dan, Sima, Anca, Catana, Cosmin, Niculescu, Loredan, Hancu, Nicolae, Gheorghe, Liana, Mihaila, Mariana, Ciurea, Silviu, Vidu, Viorica
Zdroj: Transplantation; November 2003, Vol. 76 Issue: 9 p1345-1350, 6p
Abstrakt: Domino liver transplantation is one possibility to overcome the discrepancy between the small number of liver donors and the long waiting lists. Homozygous familial hypercholesterolemia (FHC) is a genetic disorder of lipoprotein metabolism defined by the absence or small number of functional low-density lipoprotein receptors (LDL-Rs) and the ensuing high levels of serum cholesterol. We report a case of a patient with FHC whose liver was used for domino transplantation in a patient with cirrhosis and hepatocellular carcinoma.
Databáze: Supplemental Index